Description

Isradipine Lactone is a key pharmaceutical intermediate and a derivative of the calcium channel blocker isradipine. This compound matters for its critical role in the synthesis and research of cardiovascular drugs, offering a pathway to develop and refine therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical suppliers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Isradipine and related dihydropyridine calcium channel blockers.
• Active Pharmaceutical Ingredient (API) Research: Serves as a reference standard and precursor in the development and analytical testing of cardiovascular APIs.
• Chemical Synthesis: Used in organic synthesis for creating novel dihydropyridine derivatives with potential therapeutic activity.
• Analytical Standard: Employed as a high-purity standard in HPLC, LC-MS, and NMR for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Utilized in pharmacological studies to investigate calcium channel mechanisms and structure-activity relationships (SAR).

Basic Information

Product Name	Isradipine Lactone
CAS No.	1076198-34-9
Molecular Formula	C19H20N2O4
Molecular Weight	340.38 g/mol
Synonyms	4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 3-(1-Methylethyl) 5-Methyl Ester; Isradipine Impurity; Isradipine Related Compound; PN 200-110 Lactone; 4-(2,1,3-Benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Isopropyl 5-Methyl Ester; Isradipine Degradation Product
EINECS	Contact for details

Quality Control

Our Isradipine Lactone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade standards suitable for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.