Description

3-((tert-Butoxycarbonyl)Amino)-2-(Naphthalen-2-Ylmethyl)Propanoic Acid is a specialized Boc-protected amino acid derivative, serving as a crucial chiral building block in advanced organic synthesis. Its primary value lies in enabling the controlled construction of complex peptide-like structures and other bioactive molecules. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical industries, particularly for medicinal chemists and process development scientists.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Peptidomimetic Research: Used to incorporate unnatural amino acid residues into peptide backbones to enhance stability, bioavailability, and biological activity.
• Protease Inhibitor Development: Serves as a core scaffold in the design and synthesis of inhibitors targeting specific enzymes.
• Agrochemical Synthesis: Employed in the research and production of advanced, chiral agrochemicals with specific modes of action.
• Chemical Biology Probes: Utilized to create labeled or modified peptides for studying protein-protein interactions and cellular processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-fidelity chiral incorporation.

Basic Information

Product Name	3-((tert-Butoxycarbonyl)Amino)-2-(Naphthalen-2-Ylmethyl)Propanoic Acid
CAS No.	1076197-04-0
Molecular Formula	C20H25NO4
Molecular Weight	343.42 g/mol
Synonyms	Boc-3-Amino-2-(2-naphthylmethyl)propanoic acid; (R/S)-3-[(tert-Butoxycarbonyl)amino]-2-(naphthalen-2-ylmethyl)propanoic acid; 2-(2-Naphthylmethyl)-3-[(tert-butoxycarbonyl)amino]propionic acid; Boc-DL-3-Amino-2-(2-naphthylmethyl)propionic acid; N-Boc-3-amino-2-(2-naphthylmethyl)propanoic acid; 3-(Boc-amino)-2-(naphthalen-2-ylmethyl)propanoic acid; 1076197-04-0
EINECS	Contact for details

Quality Control

Our 3-((tert-Butoxycarbonyl)Amino)-2-(Naphthalen-2-Ylmethyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiomerically pure grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.