Description

(R,S)-Boc-3-Amino-2-(Naphthalen-1-Ylmethyl)-Propionic Acid is a protected amino acid derivative featuring a naphthylmethyl side chain and a tert-butoxycarbonyl (Boc) protecting group on the amine. This compound serves as a crucial chiral building block in advanced organic synthesis, enabling the controlled introduction of a sterically demanding, aromatic amino acid moiety. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel peptide-based therapeutics, enzyme inhibitors, and other bioactive molecules where structural complexity and stereochemical integrity are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Peptidomimetic Synthesis: Used to incorporate non-natural, aromatic amino acid residues into peptide chains to enhance metabolic stability, bioavailability, and target binding affinity.
• Protease Inhibitor Development: Serves as a core structural element in the design of inhibitors for various proteolytic enzymes.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged compounds for studying protein-protein interactions and enzyme mechanisms.
• Asymmetric Synthesis: Acts as a starting material or intermediate in catalytic asymmetric transformations to create complex chiral molecules.
• Material Science Research: Potential use in creating novel monomers for specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	(R,S)-Boc-3-Amino-2-(Naphthalen-1-Ylmethyl)-Propionic Acid
CAS No.	1076197-03-9
Molecular Formula	C₂₀H₂₅NO₄
Molecular Weight	343.42 g/mol
Synonyms	Boc-3-Amino-2-(1-naphthylmethyl)propanoic Acid; 2-[(1-Naphthyl)methyl]-3-[(tert-butoxycarbonyl)amino]propanoic Acid; 3-[(tert-Butoxycarbonyl)amino]-2-(naphthalen-1-ylmethyl)propanoic Acid; (R,S)-N-Boc-3-Amino-2-(1-naphthylmethyl)propionic Acid; DL-N-Boc-3-Amino-2-(1-naphthylmethyl)propionic Acid; tert-Butyl (1-((1-naphthyl)methyl)-2-carboxyethyl)carbamate; (Rac)-Boc-3-Amino-2-(Naphthalen-1-Ylmethyl)-Propionic Acid
EINECS	Contact for details

Quality Control

Our (R,S)-Boc-3-Amino-2-(Naphthalen-1-Ylmethyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and chiral analysis, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Racemic mixture
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.