Description

(S)-3-Aminobutanenitrile Hydrochloride is a high-purity chiral building block essential for the synthesis of complex pharmaceutical intermediates. Its defined stereochemistry provides a critical advantage in creating enantiomerically pure active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including potential CNS drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides for enhanced efficacy.
• Asymmetric Catalysis Research: Serves as a valuable precursor or ligand in the study and development of new chiral catalytic systems.
• Peptidomimetics & Amino Acid Derivatives: The nitrile and amine functionalities allow for transformation into non-natural amino acids and peptide analogs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high stereochemical fidelity.

Basic Information

Product Name	(S)-3-Aminobutanenitrile Hydrochloride
CAS No.	1073666-54-2
Molecular Formula	C4H8N2•HCl
Molecular Weight	120.58 g/mol (Free base: 84.12 g/mol)
Synonyms	(S)-3-Aminobutyronitrile Hydrochloride; (S)-3-Amino-1-cyanopropane Hydrochloride; (S)-4-Amino-2-butanenitrile Hydrochloride; (S)-1-Cyano-2-propylamine Hydrochloride; (S)-β-Aminobutyronitrile Hydrochloride; (S)-3-Aminobutane nitrile HCl; (S)-3-ABN•HCl
EINECS	Contact for details

Quality Control

Our (S)-3-Aminobutanenitrile Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets stringent specifications for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity (assay), chiral excess, and impurity profile is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under dry conditions to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.