Description

C-(3-Amino-Phenyl)-n-tert-Butyl-Methanesulfonamide is a specialized aromatic sulfonamide derivative characterized by its unique tert-butyl and primary amine functional groups. This compound serves as a valuable high-purity chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily required by R&D chemists and process development scientists for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and sulfonamide-based therapeutic classes.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its sulfonamide moiety for biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for introducing the tert-butylsulfonamide (Bus) protecting group or as a scaffold for further functionalization in medicinal chemistry.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced materials requiring specific aromatic amine functionalities.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	C-(3-Amino-Phenyl)-n-tert-Butyl-Methanesulfonamide
CAS No.	1073485-34-3
Molecular Formula	C11H18N2O2S
Molecular Weight	242.34 g/mol
Synonyms	N-(3-Aminophenyl)-2-methyl-2-propanesulfonamide; 3-Amino-N-tert-butylbenzenesulfonamide; N-tert-Butyl-3-aminobenzenesulfonamide; tert-Butyl (3-aminophenyl)sulfonylcarbamate (related); 1-Amino-3-[(tert-butylsulfamoyl)]benzene; Bus-protected 3-aminobenzenesulfonamide; 3-(tert-Butylsulfamoyl)aniline
EINECS	Contact for details

Quality Control

Our C-(3-Amino-Phenyl)-n-tert-Butyl-Methanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.