Description

2-Cyano-4-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is a high-value, synthetically versatile organoboron building block, essential for modern cross-coupling reactions. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of advanced materials and active pharmaceutical ingredients. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds for next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Biology Probes: Utilized to create labeled molecules and activity-based probes for studying biological pathways and protein functions.
• Polymer Chemistry: Incorporated into polymer backbones to impart unique properties like thermal stability, hydrophobicity, or specific optical characteristics.

Basic Information

Product Name	2-Cyano-4-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester
CAS No.	1073355-21-1
Molecular Formula	C₁₄H₁₅BF₃NO₂
Molecular Weight	297.08 g/mol
Synonyms	2-Cyano-4-(trifluoromethyl)benzeneboronic acid pinacol ester; [2-Cyano-4-(trifluoromethyl)phenyl]boronic acid pinacol ester; 2-Cyano-α,α,α-trifluoro-p-tolylboronic acid pinacol ester; 4-Trifluoromethyl-2-cyanophenylboronic acid pinacol ester; 2-CN-4-CF3-PhBpin; (2-Cyano-4-(trifluoromethyl)phenyl)boronic acid, pinacol ester; PINACOL 2-CYANO-4-(TRIFLUOROMETHYL)PHENYLBORONATE
EINECS	Contact for details

Quality Control

Our 2-Cyano-4-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.