Description

2-(5-Bromo-2,3,4-trifluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity, multi-functional boronic ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in enabling precise and efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly in the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing complex drug candidates, especially fluorinated and brominated compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Materials Science Research: Precursor for creating novel organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and conductive polymers.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic laboratories engaged in exploratory organic synthesis.

Basic Information

Product Name	2-(5-Bromo-2,3,4-trifluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.	1073339-18-0
Molecular Formula	C12H14BBrF3O2
Molecular Weight	329.95 g/mol
Synonyms	5-Bromo-2,3,4-trifluorophenylboronic acid pinacol ester; (5-Bromo-2,3,4-trifluorophenyl)boronic acid pinacol ester; 2-(5-Bromo-2,3,4-trifluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Bromo-2,3,4-trifluorophenyl-Bpin; 5-Br-2,3,4-F3-PhBPin; Pinacol (5-bromo-2,3,4-trifluorophenyl)boronate; CAS 1073339-18-0
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-2,3,4-trifluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is light-sensitive and easily oxidized. Keep away from heat, sparks, and open flames. The container must be kept tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.