Description

2-(2,3-Difluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1073339-17-9 is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental to constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing difluorophenyl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that benefit from the specific properties of the difluorophenyl group.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boron reagent in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Medicinal Chemistry & Drug Discovery: Enables rapid parallel synthesis and library development for screening new drug candidates in R&D laboratories.
• Ligand and Catalyst Development: Used to synthesize complex organic ligands for catalytic systems and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(2,3-Difluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1073339-17-9
Molecular Formula	C12H15BF2O2
Molecular Weight	240.06 g/mol
Synonyms	2,3-Difluorophenylboronic acid pinacol ester; (2,3-Difluorophenyl)boronic acid pinacol ester; Pinacol (2,3-difluorophenyl)boronate; 2-(2,3-Difluorophenyl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; 2,3-Difluorophenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,3-Difluorophenylboronic acid, pinacol ester; B-(2,3-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Quality Control

Our 2-(2,3-Difluorophenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards required for pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability, although the product is stable at room temperature for shorter periods. Keep the container tightly sealed under an inert atmosphere to minimize exposure to moisture and oxygen, which can affect purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.