Description

2,2'-(4,5,6-Trifluorobenzene-1,3-Diyl)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) is a high-purity, multi-fluorinated aryl bis(boronic ester) building block essential for modern cross-coupling reactions. This compound matters because it provides a reactive and versatile handle for introducing a trifluorinated aromatic core into complex molecular architectures, a critical step in developing advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex drug candidates, especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the trifluoromethylphenyl moiety can improve efficacy and environmental profile.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating electron-transport or host materials in OLED displays and lighting, where fluorination tunes electronic properties.
• Liquid Crystal & Polymer Chemistry: Incorporated into the backbone of advanced polymers and liquid crystal molecules to modify thermal stability, dielectric constant, and optical properties.
• Material Science Research: Employed in the development of Metal-Organic Frameworks (MOFs), covalent organic frameworks (COFs), and other porous materials for catalysis and gas storage.
• Chemical Biology & Probe Development: Useful for creating fluorinated tags and probes for imaging and studying biological systems.

Basic Information

Item	Details
Product Name	2,2'-(4,5,6-Trifluorobenzene-1,3-Diyl)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane)
CAS No.	1073339-14-6
Molecular Formula	C20H28B2F3O4
Molecular Weight	416.06 g/mol
Synonyms	1,3-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5,6-trifluorobenzene; 4,5,6-Trifluoro-1,3-phenylenebis(boronic acid pinacol ester); 4,5,6-Trifluorobenzene-1,3-diyldiboronic acid bis(pinacol) ester; 1,3-Bis(pinacolatoboryl)-4,5,6-trifluorobenzene; 4,5,6-Trifluoro-m-phenylenebis(boronic acid pinacol ester); 2,2'-(4,5,6-Trifluoro-1,3-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane); Trifluorinated aryl bisboronate
EINECS	Contact for details

Quality Control

Every batch of our 2,2'-(4,5,6-Trifluorobenzene-1,3-Diyl)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) is produced and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by HPLC, NMR, and other analytical techniques. Our quality commitment ensures the consistency and reliability required for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.