Description

4-Chloro-2-Fluoro-5-(Methoxycarbonyl)Phenylboronic acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a monomer or building block for creating functional polymers, liquid crystals, and organic electronic materials.
• Chemical Research: An essential reagent in academic and industrial R&D for exploring new catalytic processes and organic transformations.
• API Development: Employed in the late-stage functionalization and scale-up synthesis of Active Pharmaceutical Ingredients (APIs).
• Ligand Synthesis: Used to create sophisticated boronic acid-based ligands for catalysis and sensor development.

Basic Information

Product Name	4-Chloro-2-Fluoro-5-(Methoxycarbonyl)Phenylboronic acid
CAS No.	1073339-13-5
Molecular Formula	C8H7BClFO4
Molecular Weight	231.40 g/mol
Synonyms	(4-Chloro-2-fluoro-5-(methoxycarbonyl)phenyl)boronic acid; 5-Borono-2-chloro-4-fluorobenzoic acid methyl ester; Methyl 5-borono-2-chloro-4-fluorobenzoate; 2-Chloro-4-fluoro-5-(methoxycarbonyl)benzeneboronic acid; 4-Chloro-2-fluoro-5-(methoxycarbonyl)benzeneboronic acid; CAS 1073339-13-5; Boronic acid, B-[4-chloro-2-fluoro-5-(methoxycarbonyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-5-(Methoxycarbonyl)Phenylboronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and consistent performance in sensitive cross-coupling applications. Certificates of Analysis (COA) with full traceability are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.