Description

2-(2,5-Bis(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a critical reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures found in advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with trifluoromethylated aromatic motifs.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing trifluoromethylphenyl groups.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bis(trifluoromethyl)phenyl moiety enhances biological activity and stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Useful for incorporating fluorinated tags into molecules for studies using techniques like 19F NMR spectroscopy.
• Polymer Chemistry: Can be incorporated into polymer backbones to modify properties like thermal stability, solubility, and hydrophobicity.

Basic Information

Product Name	2-(2,5-Bis(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1073339-09-9
Molecular Formula	C14H14BF6O2
Molecular Weight	354.07 g/mol
Synonyms	2,5-Bis(trifluoromethyl)phenylboronic acid pinacol ester; (2,5-Bis(trifluoromethyl)phenyl)boronic acid pinacol ester; 2,5-Bis(trifluoromethyl)benzeneboronic acid pinacol ester; 2-(2,5-Di(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 2,5-bis(trifluoromethyl)phenylboronate; 2,5-Bis(trifluoromethyl)phenyl-Bpin; 2,5-(CF3)2C6H3Bpin
EINECS	Contact for details

Quality Control

Our 2-(2,5-Bis(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C, 19F) and HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR Purity	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.