Description

Samalizumab is a high-purity, biologically active compound identified by CAS NO 1073059-33-2, representing a significant molecule in advanced therapeutic research. Its primary value lies in its targeted mechanism of action, making it a critical reagent for immunological and oncological studies. This product is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing next-generation immunotherapies and precision medicines.

Application

• Immunotherapy Research: A key investigative tool for studying immune checkpoint modulation and T-cell function.
• Oncology Drug Discovery: Used in preclinical studies to evaluate novel cancer treatment mechanisms and efficacy.
• Biomarker Development: Serves as a reference standard in assay development for patient stratification and therapeutic monitoring.
• In Vitro Diagnostics (IVD): Employed in the development and calibration of diagnostic kits for immune-related disorders.
• Academic & Contract Research: Fundamental for basic immunological research and services within CROs (Contract Research Organizations).
• Process Development: Acts as a critical quality attribute (CQA) standard during biopharmaceutical manufacturing process optimization.

Basic Information

Product Name	Samalizumab
CAS No.	1073059-33-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Anti-ILDR2 Monoclonal Antibody; Anti-ILDR2 mAb; Immunoglobulin G1, anti-(human immunoglobulin-like domain-containing receptor 2) (human-mouse monoclonal 10C4 γ1-chain), disulfide with human-mouse monoclonal 10C4 κ-chain, dimer; 10C4 mAb; ILDR2 mAb; Monoclonal Antibody to ILDR2; Therapeutic Antibody 10C4.
EINECS	Contact for details

Quality Control

Every batch of Samalizumab is manufactured under stringent quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, potency, and consistency. Our quality protocols are designed to support regulatory filings, with testing aligned with ICH guidelines. A detailed Certificate of Analysis (COA), including data on purity, biological activity, endotoxin levels, and sterility, is provided with each shipment to guarantee traceability and compliance for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or desiccated conditions after each use to maintain stability and prevent degradation. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/MS)	Conforms to reference standard
Purity (SDS-PAGE)	≥ 95%
Purity (SEC-HPLC)	≥ 98% (Monomer)
Protein Concentration	≥ 1.0 mg/mL (or as specified)
Endotoxin	< 1.0 EU/mg
Biological Activity (Binding ELISA/SPR)	Conforms to reference
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.