Description

2-Fluoro-3-(Ethoxycarbonyl)Phenylboronic Acid is a high-purity, synthetically valuable organoboron building block. This compound matters for its critical role as a key intermediate in modern cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom and boronic acid group enable the creation of compounds with specific biological activity and stability.
• Material Science Research: Serves as a precursor for creating functionalized organic frameworks, polymers, and liquid crystals with tailored electronic or optical properties.
• Chemical Synthesis: Employed in academic and industrial R&D laboratories for constructing complex, multi-substituted biaryl and heterobiaryl structures that are difficult to access via other methods.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production, where reliable quality and consistent purity are paramount.

Basic Information

Product Name	2-Fluoro-3-(Ethoxycarbonyl)Phenylboronic Acid
CAS No.	1072952-52-3
Molecular Formula	C9H10BFO4
Molecular Weight	211.99 g/mol
Synonyms	(2-Fluoro-3-(ethoxycarbonyl)phenyl)boronic acid; 3-Borono-2-fluorobenzoic acid ethyl ester; Ethyl 3-borono-2-fluorobenzoate; 2-Fluoro-3-carbethoxyphenylboronic acid; 2-Fluoro-3-ethoxycarbonylbenzeneboronic acid; Boronic acid, B-[2-fluoro-3-(ethoxycarbonyl)phenyl]-; 1072952-52-3
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-(Ethoxycarbonyl)Phenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.