Description

2-Fluoro-5-Methylpyridine-3-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated pyridine derivatives with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides containing the fluoropyridine moiety.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid partner for coupling with various aryl/heteroaryl halides to create biaryl structures.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysts, and novel polymers.
• Chemical Biology & Medicinal Chemistry: Facilitates the rapid exploration of structure-activity relationships (SAR) in drug discovery programs.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers producing bespoke compounds for client projects.

Basic Information

Product Name	2-Fluoro-5-Methylpyridine-3-Boronic Acid
CAS No.	1072952-45-4
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	(2-Fluoro-5-methylpyridin-3-yl)boronic acid; 3-Borono-2-fluoro-5-methylpyridine; 5-Methyl-2-fluoropyridine-3-boronic acid; 2-Fluoro-5-methyl-3-pyridineboronic acid; 2-Fluoro-5-methyl-3-pyridinylboronic acid; Boronic acid, B-(2-fluoro-5-methyl-3-pyridinyl)-; 1072952-45-4
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylpyridine-3-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and development as well as cGMP environments for non-GMP use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.