Description

5-Chloro-2-Fluoro-4-Methylphenylboronic Acid is a high-purity boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in constructing biaryl structures common in many therapeutic agents.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with targeted activity and improved environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of organic light-emitting diodes (OLEDs) and liquid crystal display (LCD) components.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functional materials with specific electronic or mechanical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis.
• Suzuki-Miyaura Cross-Coupling Reactions: Primarily utilized as a boronic acid coupling partner with various aryl/vinyl halides or triflates.

Basic Information

Product Name	5-Chloro-2-Fluoro-4-Methylphenylboronic Acid
CAS No.	1072952-42-1
Molecular Formula	C7H7BClFO2
Molecular Weight	187.39 g/mol
Synonyms	(5-Chloro-2-fluoro-4-methylphenyl)boronic acid; 2-Fluoro-5-chloro-4-methylbenzeneboronic acid; 5-Chloro-2-fluoro-p-tolylboronic acid; Boronic acid, B-(5-chloro-2-fluoro-4-methylphenyl)-; 1072952-42-1; 5-Chloro-2-fluoro-4-methylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-4-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.