Description

2-Fluoro-5-Hydroxymethylphenylboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables efficient cross-coupling reactions, and the hydroxymethyl group offers a versatile handle for further chemical modification. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require fluorinated aromatic structures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of organic electronic materials, such as polymers for OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create boronic acid-based sensors and probes for detecting sugars and other biological analytes.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-5-Hydroxymethylphenylboronic Acid
CAS No.	1072952-25-0
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(2-Fluoro-5-(hydroxymethyl)phenyl)boronic Acid; 5-(Hydroxymethyl)-2-fluorobenzeneboronic Acid; 2-Fluoro-5-(hydroxymethyl)benzeneboronic Acid; 2-Fluoro-5-hydroxymethylbenzeneboronic Acid; Boronic acid, B-[2-fluoro-5-(hydroxymethyl)phenyl]-; 1072952-25-0; 2-Fluoro-5-(hydroxymethyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Hydroxymethylphenylboronic Acid is produced under a strict quality management system. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment aligns with the standards required for GMP and ISO-guided applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.