Description

2-Amino-3,5-Difluorophenylboronic Acid is a specialized bifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of an aromatic amine and a boronic acid group, enabling its use in cross-coupling reactions and as a precursor for complex heterocycles. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and pesticides with improved efficacy and selectivity.
• Material Science: Used in the development of organic electronic materials, including OLEDs and conductive polymers.
• Chemical Biology: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes and sensors.
• Ligand Synthesis: Precursor for creating novel bidentate ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new synthetic pathways.

Basic Information

Product Name	2-Amino-3,5-Difluorophenylboronic Acid
CAS No.	1072952-15-8
Molecular Formula	C6H6BF2NO2
Molecular Weight	172.93 g/mol
Synonyms	(2-Amino-3,5-difluorophenyl)boronic acid; 3,5-Difluoro-2-aminophenylboronic acid; 2-Amino-3,5-difluorobenzeneboronic acid; B-(2-Amino-3,5-difluorophenyl)boronic acid; 2-Amino-3,5-difluorophenyl-Boronic Acid; 2-Amino-3,5-difluoro phenyl boronic acid; 1072952-15-8; 2-Amino-3,5-difluorophenylboronic acid pinacol ester (related ester)
EINECS	Contact for details

Quality Control

Our 2-Amino-3,5-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.