Description

2-Amino-4,5-Difluorophenylboronic Acid is a specialized bifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of an aromatic amine and a boronic acid group, enabling efficient cross-coupling reactions and the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the development of organic electronic materials, including OLEDs and semiconductors, due to its functionalized aromatic core.
• Chemical Biology & Proteomics: Serves as a ligand for affinity chromatography and in the synthesis of molecular probes for studying biological systems.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research within R&D laboratories.

Basic Information

Product Name	2-Amino-4,5-Difluorophenylboronic Acid
CAS No.	1072952-14-7
Molecular Formula	C6H6BF2NO2
Molecular Weight	172.93 g/mol
Synonyms	2-Amino-4,5-difluorobenzeneboronic acid; (2-Amino-4,5-difluorophenyl)boronic acid; 4,5-Difluoro-2-aminophenylboronic acid; B-(2-Amino-4,5-difluorophenyl)boronic acid; 2-Amino-4,5-difluorophenyl-B(OH)2; 1072952-14-7; 2-Amino-4,5-difluoro phenyl boronic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-4,5-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.