Description

3-Carboxy-2-Fluorophenylboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a boronic acid and a carboxylic acid group on a fluorinated aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as Suzuki-Miyaura cross-coupling and the synthesis of bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial boronic acid coupling partner for forming carbon-carbon bonds, enabling the construction of complex biaryl structures common in many drug molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Employed in the development of advanced organic materials, including polymers and liquid crystals, where the functional groups allow for precise molecular engineering.
• Chemical Biology & Probe Development: Utilized for creating molecular probes and sensors that leverage boronic acid's affinity for diols, with the fluorophore potential from the aromatic fluorine.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Carboxy-2-Fluorophenylboronic Acid
CAS No.	1072952-09-0
Molecular Formula	C7H6BFO4
Molecular Weight	183.93 g/mol
Synonyms	(3-Carboxy-2-fluorophenyl)boronic acid; 2-Fluoro-3-boronobenzoic acid; 2-Fluoro-3-carboxyphenylboronic acid; 3-Borono-2-fluorobenzoic acid; Benzoic acid, 3-borono-2-fluoro-; B-(3-Carboxy-2-fluorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Carboxy-2-Fluorophenylboronic Acid is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical research and production processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.