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6-Fluoroquinolin-8-Ylboronic Acid CAS NO 1072951-44-0


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CAS No.:1072951-44-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Fluoroquinolin-8-Ylboronic Acid is a high-purity boronic acid derivative and a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

  • Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling.
  • Building block for creating novel fluorinated quinolone-based compounds with potential biological activity.
  • Precursor in material science for the development of organic electronic materials and ligands for catalysis.
  • Used in medicinal chemistry research for structure-activity relationship (SAR) studies and lead optimization.
  • Essential reagent in the synthesis of complex molecules for agrochemical discovery programs.
  • Employed in the preparation of fluorescent probes and dyes due to the quinoline scaffold.

Basic Information

Item Details
Product Name 6-Fluoroquinolin-8-Ylboronic Acid
CAS No. 1072951-44-0
Molecular Formula C9H7BBFNO2
Molecular Weight 204.97 g/mol
Synonyms 8-Borono-6-fluoroquinoline; (6-Fluoroquinolin-8-yl)boronic Acid; 6-Fluoro-8-quinolineboronic Acid; 6-Fluoro-8-boronoquinoline; B-(6-Fluoro-8-quinolinyl)boronic Acid; 6-Fluoroquinoline-8-boronic Acid; Quinoline, 6-fluoro-8-borono-; 1072951-44-0
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Quality Control

Our 6-Fluoroquinolin-8-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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