Description

2-(Methoxycarbonyl)-4-(Trifluoromethyl)Phenylboronic Acid is a high-value, synthetically versatile boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions to construct complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), especially those containing the trifluoromethyl group for enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the phenylboronic acid moiety facilitates the introduction of complex aromatic systems.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular structure is critical.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.

Basic Information

Product Name	2-(Methoxycarbonyl)-4-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1072951-42-8
Molecular Formula	C9H8BF3O4
Molecular Weight	247.97 g/mol
Synonyms	(2-(Methoxycarbonyl)-4-(trifluoromethyl)phenyl)boronic acid; Methyl 2-borono-5-(trifluoromethyl)benzoate; 2-Carbomethoxy-4-trifluoromethylphenylboronic acid; Benzoic acid, 2-borono-5-(trifluoromethyl)-, methyl ester; Methyl 2-boronobenzoate-5-trifluoromethyl; 5-Trifluoromethyl-2-methoxycarbonylphenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-(Methoxycarbonyl)-4-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.