Description

2-Fluoro-5-(Morpholine-4-Carbonyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a fluorinated aromatic ring and a morpholine amide moiety, enabling precise structural modifications. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who are developing novel active ingredients, particularly for creating complex, multi-functional molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of advanced polymers and functional organic materials.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Suzuki-Miyaura Cross-Coupling: Acts as a versatile boronic acid partner for constructing biaryl and heterobiaryl systems central to many drug candidates.

Basic Information

Product Name	2-Fluoro-5-(Morpholine-4-Carbonyl)Phenylboronic Acid
CAS No.	1072951-41-7
Molecular Formula	C11H13BFNO4
Molecular Weight	265.04 g/mol
Synonyms	(2-Fluoro-5-(morpholine-4-carbonyl)phenyl)boronic acid; 2-Fluoro-5-(morpholine-4-carbonyl)benzeneboronic acid; 2-Fluoro-5-morpholinocarbonylphenylboronic Acid; 5-Borono-2-fluoro-N-morpholinobenzamide; B-[2-Fluoro-5-(4-morpholinylcarbonyl)phenyl]boronic acid; 1072951-41-7; AKOS025310717
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Morpholine-4-Carbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.