Description

2,3,4-Trichloro-5-Nitrophenylboronic Acid is a highly functionalized boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of electron-withdrawing substituents, which make it a versatile and reactive coupling partner for the synthesis of complex, multi-substituted aromatic systems. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds prevalent in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of potential active pharmaceutical ingredients (APIs), especially those requiring halogenated, nitrated aromatic cores.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing tagged molecules or inhibitors for studying biological pathways.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects requiring precise, multi-functionalized intermediates.

Basic Information

Product Name	2,3,4-Trichloro-5-Nitrophenylboronic Acid
CAS No.	1072946-38-3
Molecular Formula	C6H3BCl3NO4
Molecular Weight	278.26 g/mol
Synonyms	(2,3,4-Trichloro-5-nitrophenyl)boronic acid; 2,3,4-Trichloro-5-nitrobenzeneboronic acid; Boronic acid, B-(2,3,4-trichloro-5-nitrophenyl)-; 5-Nitro-2,3,4-trichlorophenylboronic acid; 2,3,4-Trichloro-5-nitrophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 2,3,4-Trichloro-5-Nitrophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.