Description

Monolithium 4-Methoxypyridine-3-Boronate is a specialized organometallic reagent, specifically a lithium boronate complex, with the CAS registry number 1072946-24-7. This compound is a critical building block in modern synthetic chemistry, enabling efficient carbon-carbon bond formation through cross-coupling reactions. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require high-purity, reactive intermediates for the synthesis of complex molecules and active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based architectures.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).
• Ligand and Catalyst Development: Acts as a starting material for creating novel bidentate or polydentate ligands used in homogeneous catalysis.
• Fine Chemical Manufacturing: Employed in the scalable production of specialty chemicals, flavors, and fragrances where precise molecular control is required.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and exploring new catalytic transformations.

Basic Information

Product Name	Monolithium 4-Methoxypyridine-3-Boronate
CAS No.	1072946-24-7
Molecular Formula	C6H7BBLiNO3
Molecular Weight	164.89 g/mol
Synonyms	Lithium (4-Methoxypyridin-3-yl)boronate; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methoxypyridine Lithium Salt; 4-Methoxy-3-pyridinylboronic Acid Lithium Salt; 4-Methoxypyridine-3-boronic Acid Lithium Complex; Monolithium 4-Methoxy-3-pyridinylboronate; 3-Borono-4-methoxypyridine Lithium Salt; Li-4-MOPB
EINECS	Contact for details

Quality Control

Our Monolithium 4-Methoxypyridine-3-Boronate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B), HPLC for purity, and Karl Fischer titration for moisture content, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and oxygen-sensitive nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.