Description

(4-(Methylsulfonyl)-2-(Trifluoromethyl)-Phenyl)Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a methylsulfonyl electron-withdrawing group and a trifluoromethyl moiety, makes it an indispensable reagent for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds, which are core structures in many drug candidates targeting various diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the CF3 and SO2Me groups.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics, due to its ability to modify electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel boronic ester ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and affinity reagents for studying protein function and interactions.

Basic Information

Product Name	(4-(Methylsulfonyl)-2-(Trifluoromethyl)-Phenyl)Boronic Acid
CAS No.	1072946-16-7
Molecular Formula	C8H8BF3O4S
Molecular Weight	268.02 g/mol
Synonyms	[4-(Methylsulfonyl)-2-(trifluoromethyl)phenyl]boronic acid; 2-Trifluoromethyl-4-methylsulfonylbenzeneboronic acid; 4-Methylsulfonyl-2-trifluoromethylphenylboronic acid; (4-Methanesulfonyl-2-trifluoromethylphenyl)boronic acid; B-[4-(Methylsulfonyl)-2-(trifluoromethyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of (4-(Methylsulfonyl)-2-(Trifluoromethyl)-Phenyl)Boronic Acid is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.