Description

(3-((3,4-Difluorophenyl)Carbamoyl)-Phenyl)Boronic Acid is a high-purity, advanced pharmaceutical intermediate and a key building block in modern synthetic chemistry. This compound matters for its critical role as a boronic acid derivative in cross-coupling reactions, particularly the Suzuki-Miyaura reaction, enabling the efficient construction of complex biaryl structures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl halides and boronic acids, a cornerstone reaction in medicinal chemistry and material science.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand Synthesis for Catalysis: Serves as a building block for creating novel ligands used in asymmetric catalysis and transition metal complexes.
• Material Science & OLED Development: Employed in the research and production of organic light-emitting diodes (OLEDs) and other advanced electronic materials.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes for studying biological processes and enzyme functions.

Basic Information

Product Name	(3-((3,4-Difluorophenyl)Carbamoyl)-Phenyl)Boronic Acid
CAS No.	1072946-15-6
Molecular Formula	C13H10BF2NO3
Molecular Weight	277.03 g/mol
Synonyms	[3-[(3,4-Difluorophenyl)carbamoyl]phenyl]boronic acid; 3-((3,4-Difluorophenyl)Carbamoyl)Benzeneboronic Acid; (3-Carbamoyl-3',4'-difluorobiphenyl-3-yl)boronic acid; 3-(3,4-Difluorophenyl)aminocarbonylphenylboronic Acid; B-[3-[[(3,4-Difluorophenyl)amino]carbonyl]phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our (3-((3,4-Difluorophenyl)Carbamoyl)-Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) when possible for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.