Description

4-(Methylthio)-2-(Trifluoromethyl)Phenylboronic Acid is a specialized organoboron compound featuring both a methylthio and a trifluoromethyl substituent on the phenyl ring. This unique structure makes it a high-value building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used to construct complex molecules for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science Research: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Catalyst Ligand Synthesis: Used to prepare sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-(Methylthio)-2-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1072945-99-3
Molecular Formula	C8H8BF3O2S
Molecular Weight	236.02 g/mol
Synonyms	[4-(Methylsulfanyl)-2-(trifluoromethyl)phenyl]boronic acid; 2-Trifluoromethyl-4-methylthiobenzeneboronic acid; 4-Methylthio-2-trifluoromethylbenzeneboronic acid; (4-(Methylthio)-2-(trifluoromethyl)phenyl)boronic acid; B-[4-(Methylthio)-2-(trifluoromethyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Every batch of our 4-(Methylthio)-2-(Trifluoromethyl)Phenylboronic Acid is produced and tested under a strict quality management system. We guarantee high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening a new container to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.