Description

(3-(4-Fluoro-2-Nitrophenoxy)Phenyl)Boronic Acid is a specialized boronic acid derivative featuring a fluorinated nitrophenoxy substituent, making it a valuable building block in modern synthetic chemistry. Its core value lies in its dual functionality, serving as both a protected phenol derivative and a versatile boronic acid for cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity intermediates for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel biaryl compounds with potential therapeutic activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by enabling the construction of complex aromatic scaffolds.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for creating complex molecular architectures in medicinal and process chemistry.
• Protease Inhibitor Development: The boronic acid moiety can be utilized in the design of enzyme inhibitors, particularly for serine proteases.
• Fluorescent Probe Synthesis: The fluorinated nitroaromatic component can be leveraged in the creation of sensing molecules and imaging agents.

Basic Information

Product Name	(3-(4-Fluoro-2-Nitrophenoxy)Phenyl)Boronic Acid
CAS No.	1072945-96-0
Molecular Formula	C12H9BFNO5
Molecular Weight	293.02 g/mol
Synonyms	[3-(4-Fluoro-2-nitrophenoxy)phenyl]boronic acid; (3-((4-Fluoro-2-nitrophenyl)oxy)phenyl)boronic acid; B-[3-(4-Fluoro-2-nitrophenoxy)phenyl]boronic acid; 3-(4-Fluoro-2-nitrophenoxy)benzeneboronic acid; 3-(4-Fluoro-2-nitro-phenoxy)-phenylboronic acid; Boronic acid, B-[3-[(4-fluoro-2-nitrophenyl)oxy]phenyl]-; 1072945-96-0
EINECS	Contact for details

Quality Control

Our (3-(4-Fluoro-2-Nitrophenoxy)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in critical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.