Description

4-Formyl-3-(Trifluoromethyl)Benzeneboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, combining a formyl group and a trifluoromethyl substituent on the aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex, fluorinated active ingredients that offer enhanced biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a building block for creating sophisticated ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED and OFET components, where the trifluoromethyl group modulates electronic properties.
• Chemical Biology Probes: Utilized in the development of bioconjugation reagents and activity-based probes for protein labeling and study.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring the introduction of both aldehyde and boronic acid functionalities.

Basic Information

Product Name	4-Formyl-3-(Trifluoromethyl)Benzeneboronic Acid
CAS No.	1072944-24-1
Molecular Formula	C8H6BF3O3
Molecular Weight	217.94 g/mol
Synonyms	3-Formyl-4-(Trifluoromethyl)phenylboronic Acid; (4-Formyl-3-(trifluoromethyl)phenyl)boronic Acid; 4-Formyl-3-trifluoromethylbenzeneboronic Acid; 3-Trifluoromethyl-4-formylphenylboronic Acid; 4-Carboxy-3-(trifluoromethyl)benzeneboronic Acid (tautomeric form); 4-Formyl-3-(trifluoromethyl)benzeneboronic Acid Pinacol Ester (common protected form); 1072944-24-1
EINECS	Contact for details

Quality Control

Every batch of 4-Formyl-3-(Trifluoromethyl)Benzeneboronic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications designed for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.