Description

2-Hydroxy-3-(Trifluoromethyl)Phenyl Boronic Acid is a specialized organoboron compound featuring both a boronic acid group and a trifluoromethyl substituent on a phenolic scaffold. This unique structure makes it a highly valuable building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by R&D and production teams in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including potential active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used to create advanced herbicides and fungicides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and liquid crystal materials.
• Chemical Research: Employed in academic and industrial labs for methodological development in palladium-catalyzed coupling reactions.
• Ligand Synthesis: Useful for preparing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Libraries: Integral for constructing diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-Hydroxy-3-(Trifluoromethyl)Phenyl Boronic Acid
CAS No.	1072944-17-2
Molecular Formula	C7H6BF3O3
Molecular Weight	205.93 g/mol
Synonyms	[2-Hydroxy-3-(trifluoromethyl)phenyl]boronic acid; 3-Trifluoromethyl-2-hydroxybenzeneboronic acid; 2-Hydroxy-3-trifluoromethylbenzeneboronic acid; (2-Hydroxy-3-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[2-hydroxy-3-(trifluoromethyl)phenyl]-; 2-Borono-6-(trifluoromethyl)phenol
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-(Trifluoromethyl)Phenyl Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and elemental analysis to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.