Description

Fmoc-4-Aminohippuric Acid is a protected amino acid derivative designed for solid-phase peptide synthesis (SPPS). This compound is a crucial building block for the controlled introduction of the 4-aminohippuric acid moiety into peptide chains, enabling the synthesis of complex biomolecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for drug discovery and development projects.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of peptides, particularly those requiring the 4-aminohippuric acid residue.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics, including enzyme inhibitors and receptor ligands.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other molecules, surfaces, or carriers in bioconjugate chemistry.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Proteomics and Biochemical Research: Used as a tool compound to study protein-protein interactions and enzyme mechanisms.
• Custom Peptide Manufacturing: An essential raw material for CROs and CDMOs producing custom peptides for clients in academia and industry.

Basic Information

Product Name	Fmoc-4-Aminohippuric Acid
CAS No.	1072902-66-9
Molecular Formula	C25H22N2O6
Molecular Weight	446.45 g/mol
Synonyms	Fmoc-Ahx-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-aminohippuric Acid; 4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]benzeneacetamide Acetic Acid; Nα-Fmoc-4-aminohipuric acid; Fmoc-4-AHPA; Fmoc-protected 4-aminohippuric acid; (4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)phenyl)acetamide-2-acetic acid
EINECS	Contact for details

Quality Control

Our Fmoc-4-Aminohippuric Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.