Description

Paliperidone Benzoic Acid CAS NO 1071864-06-6 is a key pharmaceutical intermediate, specifically a benzoic acid derivative of the atypical antipsychotic paliperidone. This compound is of critical importance in the synthesis of high-purity active pharmaceutical ingredients (APIs) for the treatment of schizophrenia and schizoaffective disorder. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in the development and production of central nervous system (CNS) therapeutics.

Application

• Primary Intermediate in the commercial synthesis of Paliperidone (9-Hydroxyrisperidone) API.
• Research & Development for novel antipsychotic drug candidates and prodrug formulations.
• Process Chemistry for optimizing manufacturing routes and scaling up production.
• Quality Control as a reference standard for analytical method development and validation.
• Contract Manufacturing for pharmaceutical companies outsourcing API production.
• Academic Research in neuropharmacology and medicinal chemistry studies.

Basic Information

Product Name	Paliperidone Benzoic Acid
CAS No.	1071864-06-6
Molecular Formula	C32H35FN4O5
Molecular Weight	574.64 g/mol
Synonyms	9-Hydroxyrisperidone Benzoate; Paliperidone Benzoate; Benzoic acid, compd. with 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (1:1); (9-Hydroxyrisperidone) Benzoate; Risperidone metabolite 9-hydroxy benzoate
EINECS	Contact for details

Quality Control

Our Paliperidone Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.