Description

Benzeneacetic Acid, 2-Bromo-4-(Trifluoromethyl)-, Methyl Ester is a high-purity, synthetically valuable fluorinated aromatic building block. This compound is essential for advanced organic synthesis, where its unique combination of bromo and trifluoromethyl substituents enables precise molecular modifications. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a fluorinated building block for creating advanced organic electronic materials with tailored electronic properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings for constructing complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to introduce fluorine into polymer backbones, enhancing material properties like chemical resistance and thermal stability.

Basic Information

Product Name	Benzeneacetic Acid, 2-Bromo-4-(Trifluoromethyl)-, Methyl Ester
CAS No.	1069115-04-3
Molecular Formula	C10H8BrF3O2
Molecular Weight	297.07 g/mol
Synonyms	Methyl 2-Bromo-4-(trifluoromethyl)phenylacetate; 2-Bromo-4-(trifluoromethyl)benzeneacetic Acid Methyl Ester; [2-Bromo-4-(trifluoromethyl)phenyl]acetic Acid Methyl Ester; α-Bromo-4-(trifluoromethyl)phenylacetic Acid Methyl Ester; Methyl (2-Bromo-4-(trifluoromethyl)phenyl)acetate; 1069115-04-3; Methyl 2-Bromo-α,α,α-trifluoro-p-toluate (related structure)
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetic Acid, 2-Bromo-4-(Trifluoromethyl)-, Methyl Ester is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.