Description

2-(Perfluoropropyl)-1-Phenyl-4,5-Dihydro-1H-Imidazole is a specialized fluorinated imidazoline derivative, a high-value intermediate prized for its unique combination of lipophilicity and chemical stability imparted by the perfluoropropyl group. This compound matters for its critical role in the synthesis of advanced materials and active pharmaceutical ingredients (APIs) where fluorine incorporation is essential for modulating biological activity and material properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral therapies where fluorination improves metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine moiety to enhance pesticidal activity, rainfastness, and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, where its structure contributes to desired dielectric anisotropy, viscosity, and thermal stability in liquid crystal mixtures and organic light-emitting diode (OLED) layers.
• Surface Modification & Coatings: Employed to create fluorinated surfaces with low surface energy, leading to applications in water-repellent, oil-repellent, and anti-fouling coatings for textiles, electronics, and industrial equipment.
• Catalyst Ligand Precursor: Its imidazoline core can be utilized to develop novel chiral or non-chiral ligands for asymmetric catalysis and transition metal complexes used in fine chemical synthesis.
• Academic & Industrial Research: A valuable tool compound for investigating structure-activity relationships (SAR) and the effects of perfluoroalkyl chains on chemical and physical properties in various chemical classes.

Basic Information

Product Name	2-(Perfluoropropyl)-1-Phenyl-4,5-Dihydro-1H-Imidazole
CAS No.	1069085-53-5
Molecular Formula	C₁₂H₉F₇N₂
Molecular Weight	314.21 g/mol
Synonyms	1-Phenyl-2-(perfluoropropyl)-4,5-dihydro-1H-imidazole; 2-(Perfluoropropyl)-1-phenyl-2-imidazoline; 2-(Heptafluoropropyl)-1-phenyl-4,5-dihydro-1H-imidazole; 1-Phenyl-2-(heptafluoropropyl)imidazolidine; 2-(Perfluoropropyl)-1-phenylimidazolidine; 2-(1,1,2,2,3,3,3-Heptafluoropropyl)-1-phenyl-4,5-dihydro-1H-imidazole; PFP-Ph-Imidazoline; Perfluoropropyl phenyl imidazoline
EINECS	Contact for details

Quality Control

Our production of 2-(Perfluoropropyl)-1-Phenyl-4,5-Dihydro-1H-Imidazole adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting critical specifications. Our quality system is designed to support cGMP compliance for pharmaceutical applications and meets the rigorous standards required for advanced material synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.