Description

1-Methyl-2-(trifluoromethyl)-4,5-dihydro-1H-imidazole is a specialized heterocyclic compound featuring a unique trifluoromethylated imidazoline core structure. This compound matters as a versatile and valuable building block in advanced organic synthesis, particularly for introducing fluorine-containing motifs which are critical for modulating the physicochemical properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for creating novel nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with tailored surface properties and stability.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the behavior of fluorinated heterocycles under various conditions.

Basic Information

Product Name	1-Methyl-2-(trifluoromethyl)-4,5-dihydro-1H-imidazole
CAS No.	1069085-45-5
Molecular Formula	C5H7F3N2
Molecular Weight	152.12 g/mol
Synonyms	2-(Trifluoromethyl)-1-methyl-4,5-dihydro-1H-imidazole; 1-Methyl-2-trifluoromethyl-2-imidazoline; 4,5-Dihydro-1-methyl-2-(trifluoromethyl)-1H-imidazole; 2-Trifluoromethyl-1-methylimidazolidine; 1-Methyl-2-(trifluoromethyl)imidazoline; 2-(Trifluoromethyl)-1-methyl-4,5-dihydroimidazole
EINECS	Contact for details

Quality Control

Our 1-Methyl-2-(trifluoromethyl)-4,5-dihydro-1H-imidazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.