Description

2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-2-(Pent-4-Enyl)Hept-6-Enoic Acid is a specialized, high-purity building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel therapeutic agents and complex biomolecules. Its primary value lies in its role as a protected amino acid derivative, enabling the controlled synthesis of peptides and peptidomimetics under standard Fmoc solid-phase peptide synthesis (SPPS) conditions. This makes it an essential material for pharmaceutical R&D, biotechnology, and advanced material science applications where structural complexity and purity are paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected amino acid derivative for the controlled, sequential assembly of complex peptides and proteins in automated synthesizers.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of novel peptide-based drugs, including hormone analogs and enzyme inhibitors.
• Peptidomimetic Design: Used to incorporate non-natural, functionalized side chains into peptide backbones to enhance stability, bioavailability, and target specificity.
• Bioconjugation & Probe Development: The pent-4-enyl and hept-6-enoic acid side chains provide handles for further chemical modification, such as click chemistry, for labeling or attaching payloads.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery programs.
• Academic & Industrial Research: A valuable tool for chemists and biochemists studying protein-protein interactions, signal transduction, and structure-activity relationships (SAR).

Basic Information

Product Name	2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-2-(Pent-4-Enyl)Hept-6-Enoic Acid
CAS No.	1068435-19-7
Molecular Formula	C28H33NO4
Molecular Weight	447.57 g/mol
Synonyms	Fmoc-2-(pent-4-enyl)-2-aminohept-6-enoic acid; Fmoc-2-amino-2-(pent-4-enyl)hept-6-enoic acid; 2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-2-(pent-4-enyl)hept-6-enoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-(pent-4-enyl)-2-aminohept-6-enoic acid; Fmoc-Ahpe(Alloc) acid; Fmoc-2-amino-2-(4-pentenyl)-6-heptenoic acid; (2R/S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-(pent-4-enyl)hept-6-enoic acid (racemic mixture).
EINECS	Contact for details

Quality Control

Our production of 2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-2-(Pent-4-Enyl)Hept-6-Enoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. All material is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For short-term use (up to one month), storage at 2-8°C in a desiccated environment is acceptable. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with molecular structure
Purity (HPLC)	≥ 95.0% (Area %)
Assay (Titration)	≥ 97.0% (anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.