Description

Parstatin (Mouse) is a potent and selective inhibitor of protein disulfide isomerase (PDI), specifically targeting the A1 domain. This compound is a critical research tool for investigating the role of PDI in thrombus formation and other related biological pathways. It is essential for researchers in the fields of cardiovascular biology, hematology, and thrombosis research. The product is supplied with the CAS number 1065756-01-5.

Application

• Thrombosis Research: Used as a key pharmacological agent to study the inhibition of thrombus formation in mouse models.
• Cardiovascular Disease Studies: Investigates the role of Protein Disulfide Isomerase (PDI) in atherosclerosis, ischemia-reperfusion injury, and other vascular pathologies.
• Mechanistic Biochemistry: Elucidates the enzymatic activity and regulatory functions of PDI A1 domain in protein folding and cell signaling.
• Preclinical Drug Development: Serves as a reference compound for screening and developing novel anti-thrombotic therapeutics.
• Cell Biology Assays: Applied in in vitro studies to understand PDI's role in cancer cell survival, neurodegeneration, and infectious diseases.

Basic Information

Product Name	Parstatin (Mouse)
CAS No.	1065756-01-5
Molecular Formula	C41H54N8O10S
Molecular Weight	850.99 g/mol
Synonyms	Parstatin Mouse; NSC 83265; UNII-6K5C8J8F8F; (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(1S)-1-[[(1S)-1-amino-3-(methylsulfanyl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide
EINECS	Contact for details

Quality Control

Our Parstatin (Mouse) is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for research. Each lot undergoes comprehensive analytical testing, including identity confirmation by mass spectrometry and purity assessment by HPLC. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to support your research compliance and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.