Description

2-Cyano-3-Phenoxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic compound featuring a cyano group, a phenoxy substituent, and a trifluoromethyl group on a pyridine core. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex molecules. It is primarily utilized by R&D chemists and process development teams in the agrochemical and pharmaceutical industries for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a crucial precursor for novel pesticides, herbicides, and fungicides, leveraging the bioactivity-enhancing trifluoromethyl and pyridine motifs.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research due to its potential as a chelating or functional ligand.
• Material Science Research: Investigated as a building block for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, aromatic structure and functional handles.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	2-Cyano-3-Phenoxy-5-(Trifluoromethyl)Pyridine
CAS No.	1065607-70-6
Molecular Formula	C13H7F3N2O
Molecular Weight	264.21 g/mol
Synonyms	5-(Trifluoromethyl)-2-cyano-3-phenoxypyridine; 3-Phenoxy-5-(trifluoromethyl)picolinonitrile; 2-Cyano-3-phenoxy-5-trifluoromethylpyridine; Pyridine, 2-cyano-3-phenoxy-5-(trifluoromethyl)-; Picolinonitrile, 3-phenoxy-5-(trifluoromethyl)-; 1065607-70-6; 5-Trifluoromethyl-2-cyano-3-phenoxypyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-3-Phenoxy-5-(Trifluoromethyl)Pyridine is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.