Description

2-Chloro-N-(1-thiazol-2-ylpiperidin-3-yl)acetamide is a high-purity (98+%) organic building block with the molecular formula C10H14ClN3OS and a molecular weight of 259.76. This compound is a critical intermediate in modern pharmaceutical and agrochemical research, valued for its unique heterocyclic structure combining piperidine and thiazole moieties. It is primarily utilized by R&D chemists and process development scientists in the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Serves as a precursor in the development of new fungicides, herbicides, and insecticides with targeted modes of action.
• Chemical Biology Probe: Used in medicinal chemistry to explore structure-activity relationships (SAR) and identify new biological targets.
• Process Chemistry: Employed in route scouting and optimization for scalable API manufacturing processes.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for clients.
• Academic Research: Utilized in university laboratories for methodological studies in heterocyclic and amide bond formation chemistry.

Basic Information

Product Name	2-Chloro-N-(1-thiazol-2-ylpiperidin-3-yl)acetamide
CAS No.	1065484-55-0
Molecular Formula	C10H14ClN3OS
Molecular Weight	259.76 g/mol
Synonyms	2-Chloro-N-[1-(2-thiazolyl)-3-piperidinyl]acetamide; N-(1-(Thiazol-2-yl)piperidin-3-yl)-2-chloroacetamide; 2-Chloroacetamide, N-[1-(2-thiazolyl)-3-piperidinyl]-; 3-[(2-Chloroacetyl)amino]-1-(1,3-thiazol-2-yl)piperidine; 1-(Thiazol-2-yl)-3-(2-chloroacetamido)piperidine; CAS 1065484-55-0
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-(1-thiazol-2-ylpiperidin-3-yl)acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/LC-MS for structural confirmation, to ensure it meets the specified 98+% purity standard. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.