Description

3-Bromo-5,8-Difluoro-4-Hydroxyquinoline is a high-purity, multi-functional halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine and fluorine substituents on the quinoline core, makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for antimicrobial, anticancer, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used to develop new generations of fungicides, herbicides, and pesticides by acting as a core scaffold for bioactive molecules.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, organic semiconductors, and fluorescent materials.
• Chemical Synthesis: Versatile building block for introducing bromo, fluoro, and hydroxyquinoline motifs into more complex organic architectures via cross-coupling and substitution reactions.
• Ligand & Catalyst Development: Utilized in the design of novel chelating ligands and organocatalysts for asymmetric synthesis and metal complexation.

Basic Information

Product Name	3-Bromo-5,8-Difluoro-4-Hydroxyquinoline
CAS No.	1065087-98-0
Molecular Formula	C9H4BrF2NO
Molecular Weight	260.04 g/mol
Synonyms	4-Hydroxy-3-bromo-5,8-difluoroquinoline; 5,8-Difluoro-3-bromo-4-hydroxyquinoline; 3-Bromo-5,8-difluoroquinolin-4-ol; 4-Quinolinol, 3-bromo-5,8-difluoro-; BDFHQ
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5,8-Difluoro-4-Hydroxyquinoline is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.