Description

(S)-tert-Butyl Methyl(Pyrrolidin-3-Ylmethyl)Carbamate CAS NO 1064052-00-1 is a high-purity chiral intermediate featuring a protected pyrrolidine scaffold. This compound is of significant value in pharmaceutical research and development, serving as a critical building block for the synthesis of active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• API Synthesis: Used as a building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), where its stereochemistry is crucial for biological activity.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes to explore novel chemical space.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in asymmetric synthesis routes to introduce specific stereocenters.
• Agrochemical Research: Potential use as an intermediate in the development of novel, chiral agrochemicals such as herbicides or insecticides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity chiral intermediates.

Basic Information

Product Name	(S)-tert-Butyl Methyl(Pyrrolidin-3-Ylmethyl)Carbamate
CAS No.	1064052-00-1
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	(S)-tert-Butyl 3-((Methylamino)methyl)pyrrolidine-1-carboxylate; (S)-1-Boc-3-((Methylamino)methyl)pyrrolidine; (S)-N-Boc-N-Methyl-3-(Aminomethyl)pyrrolidine; (S)-tert-Butyl Methyl(3-Pyrrolidinylmethyl)Carbamate; (S)-1-(tert-Butoxycarbonyl)-3-((Methylamino)methyl)pyrrolidine; (S)-N-Methyl-1-Boc-3-aminomethylpyrrolidine; (S)-3-((Methylamino)methyl)-1-(tert-butoxycarbonyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl Methyl(Pyrrolidin-3-Ylmethyl)Carbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess, and impurity profiles. Our quality systems are designed to support compliance with cGMP and ICH guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.