Description

1-( 2,3-Dihydroxypropyl ) -2-Methyl-5-Nitroimidazole is a high-purity nitroimidazole derivative, a key advanced intermediate in modern pharmaceutical synthesis. This compound matters for its critical role in the development of next-generation antiprotozoal and antibacterial agents, offering a versatile building block for complex molecular architectures. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced antiparasitic and antibacterial drugs, particularly in the nitroimidazole class.
• Research & Development: Used in medicinal chemistry for the discovery and development of new therapeutic agents targeting anaerobic bacteria and protozoa.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key precursor in the multi-step synthesis of complex API molecules requiring the nitroimidazole pharmacophore.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing high-value, specialized chemical entities.
• Biochemical Research: Utilized in studies investigating the mechanism of action of nitroimidazole-based compounds and their interactions with biological targets.

Basic Information

Product Name	1-( 2,3-Dihydroxypropyl ) -2-Methyl-5-Nitroimidazole
CAS No.	1064004-83-6
Molecular Formula	C7H11N3O4
Molecular Weight	201.18 g/mol
Synonyms	2-Methyl-1-(2,3-dihydroxypropyl)-5-nitro-1H-imidazole; 1-(2,3-Dihydroxypropyl)-2-methyl-5-nitroimidazole; 2-Methyl-5-nitro-1-(2,3-dihydroxypropyl)imidazole; Dihydroxypropyl Methylnitroimidazole; Glyceryl Nitroimidazole Derivative; 5-Nitro-1-(2,3-dihydroxypropyl)-2-methylimidazole; (RS)-1-(2,3-Dihydroxypropyl)-2-methyl-5-nitroimidazole
EINECS	Contact for details

Quality Control

Our 1-( 2,3-Dihydroxypropyl ) -2-Methyl-5-Nitroimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.