Description

4-Bromo-2-Chloro-1-(Difluoromethoxy)Benzene is a high-purity, multi-functional halogenated benzene derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering unique reactivity due to its specific bromo, chloro, and difluoromethoxy substituents. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for synthesizing specialty monomers and ligands used in polymer chemistry and catalysis.
• Liquid Crystal & OLED Materials: Acts as a building block for creating halogenated aromatic cores in electronic and optoelectronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling rapid diversification of molecular structures.
• Fluorine Chemistry Studies: Valuable for research into the effects of fluorine substitution on the physicochemical properties of organic molecules.

Basic Information

Product Name	4-Bromo-2-Chloro-1-(Difluoromethoxy)Benzene
CAS No.	1062614-42-9
Molecular Formula	C7H4BrClF2O
Molecular Weight	257.46 g/mol
Synonyms	1-Bromo-4-chloro-2-(difluoromethoxy)benzene; 2-Chloro-4-bromo-1-(difluoromethoxy)benzene; Benzene, 4-bromo-2-chloro-1-(difluoromethoxy)-; 4-Bromo-2-chloro-α,α-difluoroanisole; 1-(Difluoromethoxy)-4-bromo-2-chlorobenzene; 2-Chloro-α,α-difluoro-4-bromoanisole; 4-Bromo-2-chlorophenyl difluoromethyl ether
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-1-(Difluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment ensures batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended long-term storage temperature is between 2°C and 8°C. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.