Description

(4-Fluoro-2-(Hydroxymethyl)Phenyl)Boronic Acid is a high-purity, functionalized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a boronic acid group and a hydroxymethyl substituent on a fluorinated aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is primarily utilized in Suzuki-Miyaura cross-coupling reactions to create novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used to construct fluorinated heterocycles and complex molecules for next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a starting material for creating sophisticated bidentate ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of fluorinated organic electronic materials, such as OLED emitters and charge-transport layers.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes and tags for studying biological processes and protein interactions.
• Library Synthesis for Drug Discovery: A valuable building block for high-throughput and combinatorial chemistry to generate diverse fluorinated compound libraries for screening.

Basic Information

Product Name	(4-Fluoro-2-(Hydroxymethyl)Phenyl)Boronic Acid
CAS No.	1061223-45-7
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(4-Fluoro-2-(hydroxymethyl)phenyl)boronic acid; 2-(Hydroxymethyl)-4-fluorobenzeneboronic acid; 4-Fluoro-2-(hydroxymethyl)benzeneboronic acid; (4-Fluoro-2-hydroxymethylphenyl)boronic acid; Boronic acid, B-[4-fluoro-2-(hydroxymethyl)phenyl]-; CAS 1061223-45-7
EINECS	Contact for details

Quality Control

Our (4-Fluoro-2-(Hydroxymethyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.