Description

2-((Dimethylamino)Methyl)-4-Fluorophenylboronic Acid is a sophisticated boronic acid derivative featuring both a dimethylamino-methyl and a fluorine substituent on the aromatic ring. This bifunctional structure makes it a highly valuable building block in modern synthetic chemistry, particularly for cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds. Its unique substitution pattern allows for the introduction of specific molecular features critical for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for constructing biaryl and heterobiaryl structures, which are core scaffolds in many functional molecules.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is required.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	2-((Dimethylamino)Methyl)-4-Fluorophenylboronic Acid
CAS No.	1061223-43-5
Molecular Formula	C9H13BFNO2
Molecular Weight	197.02 g/mol
Synonyms	4-Fluoro-2-((dimethylamino)methyl)benzeneboronic Acid; (4-Fluoro-2-((dimethylamino)methyl)phenyl)boronic Acid; 2-(Dimethylaminomethyl)-4-fluorophenylboronic Acid; 4-Fluoro-2-(N,N-dimethylaminomethyl)phenylboronic Acid; B-[4-Fluoro-2-[(dimethylamino)methyl]phenyl]boronic Acid; 1061223-43-5; AKOS006361889
EINECS	Contact for details

Quality Control

Our 2-((Dimethylamino)Methyl)-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.