Description

1-Bromo-2-Iodo-3-(Trifluoromethoxy)Benzene is a high-value, multi-halogenated aromatic building block designed for advanced synthetic chemistry. This compound matters because it provides a unique combination of bromine, iodine, and trifluoromethoxy substituents on a benzene ring, enabling precise, sequential cross-coupling reactions and the introduction of fluorine-containing motifs. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as in materials science for creating specialized organic electronic components.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the trifluoromethoxy group is a critical pharmacophore.
• Material Science Research: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic electronic materials due to its halogenated and fluorinated structure.
• Cross-Coupling Reactions: The differentiated halogen atoms (Br and I) allow for selective, step-wise metal-catalyzed couplings (e.g., Suzuki, Stille, Sonogashira) to construct complex, polyfunctionalized arenes.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis or as a scaffold for creating metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a starting material for synthesizing fluorescent tags or molecular probes used in biochemical assays and imaging.

Basic Information

Product Name	1-Bromo-2-Iodo-3-(Trifluoromethoxy)Benzene
CAS No.	1060691-36-2
Molecular Formula	C7H3BrF3IO
Molecular Weight	366.90 g/mol
Synonyms	2-Bromo-1-Iodo-3-(Trifluoromethoxy)Benzene; 3-Bromo-2-Iodo-1-(Trifluoromethoxy)Benzene; Benzene, 1-bromo-2-iodo-3-(trifluoromethoxy)-; 1-Bromo-2-iodo-3-(trifluoromethoxy)benzene; 3-(Trifluoromethoxy)-1-bromo-2-iodobenzene; 2-Iodo-3-bromotrifluoromethoxybenzene; 1-Bromo-2-iodo-α,α,α-trifluoro-3-methoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Iodo-3-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.