Description

2-(5-Bromo-2-Chlorophenyl)Acetonitrile is a high-purity halogenated phenylacetonitrile derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its versatile reactivity, particularly in the construction of complex heterocyclic and pharmaceutical intermediates. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing substituents.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs engaged in producing bespoke compounds for client projects.

Basic Information

Product Name	2-(5-Bromo-2-Chlorophenyl)Acetonitrile
CAS No.	1057216-52-0
Molecular Formula	C8H5BrClN
Molecular Weight	230.49 g/mol
Synonyms	(5-Bromo-2-chlorophenyl)acetonitrile; 2-Chloro-5-bromobenzyl cyanide; 5-Bromo-2-chlorobenzyl cyanide; (5-Bromo-2-chlorophenyl)ethanenitrile; α-Cyano-5-bromo-2-chlorotoluene; 2-(5-Bromo-2-chlorophenyl)ethanenitrile; 1057216-52-0; 2-(5-Bromo-2-chloro-phenyl)-acetonitrile
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-2-Chlorophenyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.