Description

(tert-Butoxy)Carbonyl D-2-Chloro-4-Fluorophe is a high-purity, chiral building block primarily used in advanced pharmaceutical synthesis. This compound is critical for the development of active pharmaceutical ingredients (APIs) and fine chemicals where stereochemical integrity is paramount. It is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• API (Active Pharmaceutical Ingredient) Development: Used in the construction of complex molecular scaffolds for potential therapeutics.
• Agrochemical Synthesis: Serves as a building block for creating advanced, optically active pesticides and herbicides.
• Peptide Chemistry: Can be utilized in the preparation of modified amino acid derivatives and peptide mimetics.
• Asymmetric Synthesis: Employed as a reagent or intermediate in catalytic asymmetric transformations to introduce chirality.
• Chemical Research & Development: A valuable tool for academic and industrial R&D in organic and process chemistry.

Basic Information

Product Name	(tert-Butoxy)Carbonyl D-2-Chloro-4-Fluorophe
CAS No.	1056934-68-9
Molecular Formula	C11H12ClFO3
Molecular Weight	246.66 g/mol
Synonyms	Boc-D-2-Chloro-4-fluorophenylalanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(2-chloro-4-fluorophenyl)propanoic acid; D-Boc-2-Chloro-4-fluorophenylalanine; (R)-3-(2-Chloro-4-fluorophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid; Boc-D-2-Cl-4-F-Phe; N-Boc-D-2-Chloro-4-fluorophenylalanine; (R)-N-Boc-2-Chloro-4-fluorophenylalanine; D-2-Chloro-4-fluorophenylalanine tert-butyl ester
EINECS	Contact for details

Quality Control

Our (tert-Butoxy)Carbonyl D-2-Chloro-4-Fluorophe is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure high enantiomeric purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to guarantee compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.