Description

3-(Bromomethyl)Phenylsulphur Pentafluoride, also known as 1-(Bromomethyl)-3-(Pentafluorosulphanyl)Benzene, is a high-value organofluorine and organobromine building block essential for advanced chemical synthesis. This compound is prized for its unique combination of a reactive bromomethyl handle and a stable, lipophilic pentafluorosulfanyl (SF5) group, enabling precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting CNS disorders, where the SF5 group can improve metabolic stability and membrane permeability.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides, leveraging the SF5 moiety's influence on biological activity and environmental fate.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced functional materials, where the introduction of the SF5 group can fine-tune electronic properties, thermal stability, and mesomorphic behavior.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalysis, utilizing the bromomethyl site for attachment to metal centers or scaffolds.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to incorporate fluorine-rich segments into polymers, enhancing chemical resistance, surface properties, and durability.
• Radiolabeling & Tracer Synthesis: The bromine atom provides a potential site for isotopic exchange (e.g., with 76Br, 77Br) for use in Positron Emission Tomography (PET) imaging agents.

Basic Information

Item	Details
Product Name	3-(Bromomethyl)Phenylsulphur Pentafluoride / 1-(Bromomethyl)-3-(Pentafluorosulphanyl)Benzene
CAS No.	1056893-24-3
Molecular Formula	C7H6BrF5S
Molecular Weight	273.09 g/mol
Synonyms	1-(Bromomethyl)-3-(pentafluoro-λ6-sulfanyl)benzene; 3-(Bromomethyl)benzenesulfonyl pentafluoride; 3-(Bromomethyl)phenylsulfur pentafluoride; α-Bromo-3-(pentafluorosulfanyl)toluene; 3-(Bromomethyl)SF5-Benzene; m-(Bromomethyl)phenylsulfur pentafluoride; (3-Bromomethylphenyl)sulfur pentafluoride
EINECS	Contact for details

Quality Control

Our production of 3-(Bromomethyl)Phenylsulphur Pentafluoride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development. Each lot undergoes comprehensive analytical characterization, including NMR (1H, 13C, 19F), HPLC, and GC analysis, to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We operate under a quality management system and can support development projects requiring compliance with cGMP or other regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.