Description

3',4',5'-Trifluoro-2-Nitrobiphenyl is a high-value fluorinated aromatic intermediate characterized by its unique biphenyl core substituted with nitro and trifluoro groups. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific fluorine substitution pattern imparts desirable electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and optical properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening.

Basic Information

Product Name	3',4',5'-Trifluoro-2-Nitrobiphenyl
CAS No.	1056196-56-5
Molecular Formula	C12H6F3NO2
Molecular Weight	241.18 g/mol
Synonyms	2-Nitro-3',4',5'-trifluorobiphenyl; [1,1'-Biphenyl]-2-nitro-3',4',5'-trifluoro; 3',4',5'-Trifluoro-2-nitro-1,1'-biphenyl; 2-Nitro-3,4,5-trifluorobiphenyl; 3,4,5-Trifluoro-2-nitrobiphenyl; Biphenyl, 2-nitro-3',4',5'-trifluoro-
EINECS	Contact for details

Quality Control

Every batch of 3',4',5'-Trifluoro-2-Nitrobiphenyl is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and mass spectrometry, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.